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Archive for the ‘Cholesterol’

Zocor review: Decreasing of cholesterol level

June 02, 2008 By: admin Category: Cholesterol No Comments →

What is Zocor?

Zocor (Simvastatin) is one of the most effective, safe preparations for decreasing of cholesterol level. This preparation concerns to statins group and is the most prescribed preparation from this group in the world.

Statins reduce the content of cholesterol in blood suppressing its synthesis in organism. Middle-aged patients who intaked statins had decreased the risk of ischemic heart disease development. Statins reduce pathological changes in a myocardium, reduce risk of lethal outcome from coronary vessels diseases and general death rate. Statins can be also used as preventive measures of an atherosclerosis.

Zocor indications

High cholesterol level (hypercholesterolemia), combined hypercholesterolemia and triglyceridemia, ischemic heart disease, preventive measures for myocardial infarction and cerebral infarction, atherosclerosis.

Pharmacological action of Zocor

Zocor reduces low-density lipoprotein (LDL) cholesterol and total cholesterol level in blood.

It reduces concentration of triglycerides.

The patients who suffer from stenocardia or have a heart attack, had improvement of blood plasma (due to reduction a cholesterol level) and improved parameters of survival rate after Zocor therapy.

Zocor has it’s own anti-ischemic action, connected with reducing lipid level and anti-inflammatory effect of preparation.

Clinical researches of Zocor:

Scandinavian Simvastatin Survival Study:

This research has proved efficiency of statins (by the example of zocor) during secondary preventive measures for ischemic heart disease. There has been noticed a decrease in general death rate from ischemic heart disease by 42%, reduction of frequency of the basic cardiovascular complication by 34%, decrease myocardial infarction by 37% after zocor therapy. Simvastatin was also effective for treatment women and persons older than 60.

Heart Protection Study:

  Simvastatin therapy has proved the efficiency in comparison with placebo irrespective of sex and age of patients, irrespective of presence or absence of ischemic heart disease and pancreatic [insular] diabetes.

The patients who took this preparation, decreased the risk of serious cardiovascular catastrophe by 24 % irrespective of age, sex, an initial level of cholesterol, and also other concomitant diseases.

One of the most remarkable results of research is authentic reduction in insults by 25 %.

Zocor has also successfully passed research on safety Comparative HDL Efficacy and Safety Study.

Important information about zocor

Do not use this medication if you are allergic to simvastatin, if you are pregnant or breast-feeding, or if you have liver disease.

Dosage of Zocor

Intake before meal: in the beginning of a therapy in a doze of 5-10 mg a day, if necessary up to 40 mg a day depending on the content of cholesterol and lipoproteids in blood.

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Side effects of Zocor

diarrhea, wind, nausea, headache, convulsions, myalgia, allergic reactions.

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Why the cholesterol is dangerous and how to decrease the cholesterol level ?

May 13, 2008 By: admin Category: Cholesterol No Comments →

What is cholesterol?

Cholesterol is a substance similar to fat which is formed in a liver and gets in organism with some products. Cholesterol is necessary for organism: it is a part of body cells. Cholesterol is used for synthesis of hormones, vitamin D and acids required for digestion.

A small amount of cholesterol is quite enough for organism.

How does the level of cholesterol raise in blood?

The main cause of the cholesterol level increasing is the food rich in saturated fats or cholesterol. Other reasons can be:

- The hereditary problems connected with inability of organism to process cholesterol.

How to decrease the cholesterol level?
- The disease which causes increase of a cholesterol level (diabetes, renal disease, disease of liver or hypothyroidism) .

Why is high level of cholesterol in blood dangerous?

The increased level of cholesterol does not cause any symptoms; therefore many people do not suspect they have too high cholesterol level in blood. Surplus of cholesterol is accumulated at the walls of arteries and cause formation of plaques, which narrow vessels. Thus develops the atherosclerosis. Big plaques or complicated plaques with blood clots can completely block arteries that hinder from blood flow. Thus delivery of oxygen and nutrients to the tissues is broken; it leads to their dying off.

It causes development of heart attack or brain insult.

What factors raise risk of cardiovascular diseases’ development?

High arterial pressure, smoking, excess weight, high level of cholesterol, inert way of life, diabetes, hypertrophy of heart, renal diseases, excess use of kitchen salt.

How to decrease the cholesterol level?

To conduct active way of life, to stop smoking, learn to manage stress, to reduce excess weight.

However diets and physical exercises can be insufficient for effective decrease of cholesterol level. There are preparations which help to reduce amount of harmful cholesterol.

How to decrease the cholesterol level?
The most effective and proved preparations for lowering the level of cholesterol:

Lipitor

Lipostatin

Cholestoplex

Shuddha Guggulu

Lasuna

Tricor

Lopid

Zocor